Accelerate Biotech Innovation with Custom Software
From LIMS to clinical trial management, Bookuvai builds GxP-compliant biotech software that accelerates research, regulatory submissions, and time to market.
Industry: Biotech
Pain Points
- GxP Validation Requirements: Biotech software must meet FDA 21 CFR Part 11 and EU Annex 11 requirements for electronic records and signatures. Validation protocols (IQ/OQ/PQ) add months to deployment timelines.
- Complex Data Pipelines: Genomics, proteomics, and high-throughput screening generate terabytes of data that must be processed, analyzed, and stored with full traceability and audit trails.
- Siloed Research Data: Research teams often use disconnected spreadsheets, ELNs, and LIMS that make cross-experiment analysis, data sharing, and regulatory submission assembly painfully manual.
Solutions
- Laboratory Information Management (LIMS): Custom LIMS platforms that track samples, experiments, and results with chain of custody, instrument integration, and regulatory-compliant audit trails.
- Sample chain of custody tracking
- Instrument data auto-capture
- SOP-driven workflow enforcement
- 21 CFR Part 11 electronic signatures
- Clinical Trial Data Platforms: EDC-adjacent platforms for capturing, cleaning, and analyzing clinical trial data with protocol deviation tracking and regulatory submission packaging.
- Electronic data capture forms
- Protocol deviation management
- Data query and cleaning workflows
- Bioinformatics Pipelines: Scalable data processing pipelines for genomic sequencing, protein analysis, and compound screening with visualization dashboards for researchers.
- Nextflow/Snakemake pipeline orchestration
- Sequence alignment and variant calling
- Interactive result visualization
- Cloud-based elastic compute scaling
Use Cases
- Custom LIMS for Cell Therapy Lab — A LIMS tracking cell therapy manufacturing from donor sample receipt through processing, testing, release, and shipping with full GMP compliance. (250-350, $500-$700, 12-16 weeks)
- Clinical Trial Dashboard — A dashboard for clinical operations teams to monitor enrollment progress, protocol deviations, adverse events, and site performance across trial sites. (180-260, $360-$520, 10-12 weeks)
- Genomic Data Analysis Portal — A web portal for researchers to upload sequencing data, run analysis pipelines, visualize results, and collaborate on findings with audit-logged access control. (160-240, $320-$480, 8-12 weeks)
Compliance Notes
- FDA 21 CFR Part 11 electronic records and signatures
- GxP Good Practice guidelines (GLP, GCP, GMP)
- EU Annex 11 computerized systems validation
Frequently Asked Questions
- Can you build 21 CFR Part 11 compliant software?
- Yes. We implement electronic signatures, audit trails, access controls, and data integrity measures that satisfy Part 11 requirements. We also generate IQ/OQ/PQ validation documentation.
- Do you handle genomic data at scale?
- We build bioinformatics pipelines on AWS Batch or Google Life Sciences that process terabytes of sequencing data. We use Nextflow for pipeline orchestration and S3/GCS for data lake storage.
- Can you integrate with our existing ELN?
- We integrate with Benchling, LabArchives, and other ELN platforms via their APIs to connect electronic notebook data with LIMS, analytics pipelines, and regulatory submission workflows.
- How do you handle validation for regulated biotech software?
- We follow GAMP 5 software categorization and produce validation protocols (IQ, OQ, PQ), traceability matrices, and risk assessments as part of the delivery. We work with your QA team to execute validation.